5-Amino-1MQ

A small molecule that blocks the enzyme NNMT, studied for boosting cellular NAD+ and metabolism, with interest in fat loss and muscle health.

What it is

5-Amino-1MQ is a small molecule (not a peptide) studied for its ability to inhibit NNMT — an enzyme that becomes overactive in fat tissue and is linked to slowed metabolism. It's grouped here for its metabolic research role.

How it's thought to work

By blocking NNMT, 5-Amino-1MQ is thought to raise cellular levels of NAD+ and a metabolite called MNA, shifting fat cells toward burning energy rather than storing it. Higher NAD+ is broadly associated with healthier cellular metabolism.

Potential health benefits

Investigated for:

Reducing fat storage and supporting fat loss.
Improved metabolic health via NAD+ pathways.
Muscle preservation in some research models.

What the research says

Animal studies show NNMT inhibition can reduce adiposity and improve metabolic markers. 5-Amino-1MQ is an active research area, but human clinical data is still limited and early.

Considerations

A research compound. Given the early human evidence, qualified medical guidance is recommended.